Isco was injured in a friendly match against Malaga. Betis confirmed that the player had a fibula fracture in his left leg and was expected to be missing for 3 months.

According to Opta statistics, last season Isco lost 7 in 32 games, with a loss rate of 22%. In the absence of Isco, Betis lost 8 in 27 games, with a loss rate of 30%.