At 0:00 a.m. on October 6, in the 6th round of the Serie A, Napoli will face Genoa at home. Sky Sports in Italy said that De Bruyne will take a rest in this game, and Napoli will resume the 433 formation commonly used last season. After introducing De Bruyne this season, Napoli previously focused on the 451 formation, with De Bruyne and McTominay taking turns to play left midfielder.

Italian Sky Sports predicts the start of this round of Serie A:

Naples 433: Vania; Di Lorenzo, Buickma, Juan Jr., Oliveira; Anguysa, Loboteca, McTominay; Politano, Hoillen, Nerez

Genoa 4231: Leali; Sabelie, Erstigo, Vasquez, Marin; Massini, Frendrup; Kufe, Caboni, Eletson; Colognebo